Keep track of people which have a history of despair and don't re-administer Depo-Provera CI if despair recurs.
The mixture of MPA with aminoglutethimide to deal with metastases from breast cancer is related to an increase in melancholy.[28] St John's wort could reduce the usefulness of MPA as a contraceptive due to acceleration of its metabolism.[70]
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You could continue to be on Depo-Provera for about two yrs. It may possibly weaken your bones, which improves your hazard of osteoporosis. Your Health care service provider may perhaps propose switching to a special type of start Handle or possessing a bone density exam if you wish to maintain employing it following two decades.
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Depo-Provera is made use of to avoid pregnancy and manage clinical circumstances associated with the menstrual cycle. A healthcare Experienced may well counsel Depo-Provera if:
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Switching from an IUD: As well as the need for back again-up contraception when starting off DMPA, there is likely to be additional issues when switching from an IUD. In the event the individual has experienced sexual intercourse due to the fact the beginning in their current menstrual cycle and it has been >5 times since menstrual bleeding started, theoretically, residual sperm may be inside the genital tract, which may lead to fertilization if ovulation happens.
Timing: The 1st DMPA injection could possibly be administered at any time if it is reasonably selected that the affected individual will not be pregnant (Box three).
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